Thyroid Cancer:

Thyroid cancer is a cancerous growth
of the thyroid gland.


VANDETANIB EXTENDS SURVIVAL
TIME WITH THYROID CANCER
Results of a study involving an
experimental AstraZeneca PLC drug,
vandetanib, showed it extends the time
before a type of rare thyroid cancer
gets worse.

Vandetanib works to block a protein
involved with cancer growth as well as
block blood vessels that feed tumors.
One of the proteins the drug targets is
known as RET, which appears to be
involved in a certain type of thyroid
cancer known as medullary thyroid
cancer. The thyroid gland is located at
the base of the neck and makes
hormones that control heart rate, body
temperature and metabolism.

Vandetanib was previously studied as
a treatment for advanced non-small
cell lung cancer in combination with
chemotherapy.
AstraZeneca's study involved 331
patients with advanced medullary
thyroid cancer.

AstraZeneca is also conducting
another trial in a more common form of
papillary thyroid cancer.