Melanoma Prevention and Management

Melanoma is a type of skin cancer with a high risk of fatality, but its incidence can be significantly reduced through proactive preventive measures. Studies show that over 90% of melanoma cases are related to long-term ultraviolet (UV) exposure, thus prevention strategies must address environmental, behavioral, and genetic risks comprehensively. A combination of regular skin checks and healthy habits can effectively lower the threat of malignant melanoma.

The key to preventing melanoma lies in the dual approach of "risk factor management" and "early detection." Daily protective measures include using physical sunscreens, avoiding sun exposure, and establishing a habit of skin self-examination. Additionally, individuals with genetic predispositions should start systematic protection earlier and undergo regular professional screenings by specialists.

Risk Factor Management

Ultraviolet Protection

Ultraviolet (UV) radiation is the most critical environmental factor leading to melanoma. Daily protection should include:
1. Choosing broad-spectrum sunscreen products with SPF 50+, reapplying every two hours
2. Wearing long-sleeved clothing, wide-brimmed hats, and sunglasses during outdoor activities
3. Avoiding outdoor exposure during peak UV hours from 10 AM to 2 PM

  • Wearing UPF 50+ clothing can block 98% of UVA/UVB
  • Vehicle and indoor glass cannot block UVA, so special attention should be paid to side window exposure

Genetic Risk Management

Family history is an important focus for prevention: if a first-degree relative (parents, siblings) has had melanoma, the individual's risk increases by 2-3 times. Genetic counseling is recommended, and full-body skin checks should be conducted every six months starting at age 20. Genetic testing can assess mutations in relevant genes such as CDKN2A.

High-risk groups should establish a "daily skin self-examination" habit, paying special attention to areas often overlooked, such as palms, soles, and hairlines. It is recommended to use the "ABCDE rule" for self-monitoring:

  • A (Asymmetry): Are the two halves of the mole symmetrical?
  • B (Border): Are the edges irregular or blurred?
  • C (Color): Is the color variable or suddenly deepening?
  • D (Diameter): Is the diameter greater than 6 millimeters?
  • E (Evolution): Are there ongoing changes in shape, size, or color?

Lifestyle Adjustments

Modern lifestyle patterns are significantly correlated with melanoma risk. Research indicates that frequent exposure to artificial UV (such as tanning beds) increases the risk by 75%. Adjusting the following behaviors can effectively reduce risk:

  • Completely avoid using tanning beds and UV tanning devices
  • Adopt a "shade strategy" during outdoor activities, using umbrellas or seeking shaded areas
  • Conduct preventive skin checks before each summer

In urban environments, secondary UV exposure from reflective surfaces (such as glass facades) is often overlooked. It is recommended to wear UPF clothing and use physical sunscreens containing zinc oxide when active in high-reflectance areas.

Dietary Recommendations

Antioxidant Nutrient Intake

Consuming a diet rich in antioxidants can slow down DNA damage caused by UV radiation. It is recommended to consume daily:

  • Dark-colored fruits and vegetables (such as blueberries, spinach, purple cabbage)
  • Deep-sea fish rich in Omega-3 fatty acids (salmon, mackerel)
  • Vitamin D and folic acid supplements (follow physician's recommended dosage)

Excessive intake of animal fats and refined sugars may weaken the skin's repair mechanisms. It is advised to adjust dietary composition to: 60% phytochemical sources, 20% high-quality proteins, 20% whole grains, and to avoid chemical additives in processed foods.

Dietary Restrictions and Supplements

Some herbal supplements may enhance protective effects but should be used under medical supervision. The combination of vitamins C and E has been shown to enhance skin cell repair capabilities. It is necessary to avoid excessive intake of supplements containing photosensitive ingredients (such as St. John's Wort), as these substances may exacerbate UV damage.

Exercise Guidelines

Regular exercise can enhance the immune system's ability to monitor abnormal cells, but skin protection during exercise is essential. Recommendations include:

  • Schedule outdoor exercise in the early morning or late evening
  • Use waterproof sunscreen and reapply every hour
  • Choose sportswear with UPF 50+

High-intensity interval training (HIIT) has been shown to enhance natural killer cell activity, but the skin should be cleaned immediately after exercise and monitored for signs of sunburn. When swimming, it is recommended to use waterproof sunscreen and rinse off immediately after getting out of the water, followed by reapplication.

Regular Screening

Self-Examination Techniques

Conduct a full-body skin self-exam monthly, using a full-length mirror and a handheld mirror to check hard-to-see areas. The examination steps include:

  1. Front chest, back, and outer sides of limbs
  2. Between fingers, nail beds, and soles of feet
  3. Hairline, behind ears, and private areas

It is recommended to use a "skin map" recording method, taking photos to document changes in the shape and size of moles. Abnormal signs include: rapid expansion, non-healing ulcers, or sudden color deepening, which should prompt immediate medical attention.

Professional Screening Frequency

Individuals at average risk should have a professional skin examination once a year, while high-risk individuals (with a family history/sunburn history) should be checked every six months. Physicians may use a dermatoscope or whole-body imaging system for precise scanning, as early detection can improve the treatment success rate by 95%.

Environmental or Workplace Considerations

Specific occupations (such as beach workers, pilots) have high UV exposure and require enhanced protective measures. Recommendations include:

  • Pilots should use UV-protective goggles
  • Outdoor workers should reapply sunscreen every hour
  • Construction workers should be equipped with UV-protective shading devices

Indoor workers should also be aware that glass cannot block UVA, and it is recommended to install UV-blocking films on office windows and use UV-protective eyewear in front of computer screens.

When to Consult a Healthcare Professional

Seek immediate medical attention when the following situations occur:
1. Significant changes in the shape or color of existing moles within 1-2 months
2. New skin lesions accompanied by itching or bleeding
3. Family history with moles that meet the "crow's feet" (irregular borders) criteria

Individuals over 40 or in high-risk groups should undergo genetic predisposition assessments annually, and physicians may recommend whole-body imaging examinations or liquid biopsy techniques. Any unexplained skin ulcers that have not healed for over two weeks should undergo immediate tissue biopsy.

By integrating environmental protection, behavioral adjustments, and regular screenings, the preventability of melanoma can exceed 70%. Establishing a personalized protection system and maintaining communication with the healthcare team are key strategies for reducing disease risk.

 

Frequently Asked Questions

How can I determine if a mole on my skin has melanoma risk?

You can observe using the "ABCDE" principle: A (Asymmetry) abnormal moles may have asymmetrical shapes; B (Border) edges are irregular or blurred; C (Color) color is uneven; D (Diameter) exceeds 6 millimeters; E (Evolution) shape, size, or color changes in a short time. If multiple features are present, seek immediate medical examination.

Besides sunscreen, what other ways can reduce melanoma risk in daily life?

Avoid sun exposure during high UV index periods (10 AM to 2 PM) and wear wide-brimmed hats, long-sleeved clothing, and UV-protective sunglasses. Additionally, regularly self-examine the skin, especially on areas like the back and legs that are often overlooked, to help detect abnormal changes early.

Are individuals with a strong immune system less likely to develop melanoma?

The immune system's function is somewhat related to melanoma development, but it is not absolute. The immune system can help identify and eliminate abnormal cells, but long-term UV exposure or genetic factors may still increase risk. Therefore, even with a healthy immune system, strict adherence to sun protection measures and regular check-ups is necessary.

If there is a family history of melanoma, what specific details should be paid attention to in daily protection?

Individuals with a family history should have professional skin checks every 3-6 months and enhance daily sun protection by using broad-spectrum sunscreen with SPF 30 or higher, reapplying every 2 hours. Additionally, avoid using UV lamps or tanning beds to reduce the chance of triggering genetic mutations.

Do I still need sunscreen in winter or on cloudy days to prevent melanoma?

Yes. UVA in UV radiation can penetrate clouds, causing DNA damage to the skin and increasing melanoma risk. Even in cold or cloudy weather, sunscreen should still be applied when going outside, along with protective clothing. The UV reflection from snowy ground in winter can also enhance exposure effects, so caution is necessary.

Melanoma