The diagnosis of migraine primarily relies on clinical evaluation and medical history analysis, as there are currently no specific biomarkers to directly confirm the diagnosis. Physicians will systematically inquire about symptoms and descriptions to rule out other possible diseases and assess according to the diagnostic criteria established by the International Headache Society. An early and accurate diagnosis can help patients develop a management plan promptly, preventing symptom exacerbation.
The diagnostic process typically consists of three stages: initial assessment to screen for possible headache types, detailed analysis of symptoms and lifestyle, and finally, necessary examinations to rule out other serious diseases. Patients should prepare information such as past symptom records, medication history, and family medical history to enhance diagnostic efficiency.
Clinical evaluation is at the core of migraine diagnosis. Physicians will systematically ask about the nature and pattern of symptoms, including the frequency, duration, location, and intensity of headaches. Key questions include whether symptoms are accompanied by nausea, vomiting, light sensitivity (photophobia), or sound sensitivity (phonophobia), which are typical accompanying symptoms. For instance, if headaches occur alongside visual disturbances such as flashing lights or aura symptoms, it may meet the diagnostic criteria for migraine with aura.
Physicians will assess the impact of symptoms on daily life, such as whether they lead to reduced activity or impaired occupational function. Additionally, family history investigation is essential, as genetic predisposition is a significant risk factor for migraines. During the medical history collection, it is necessary to distinguish headache triggers, such as specific foods, stress, changes in sleep patterns, or hormonal fluctuations.
Although migraines themselves are not organic lesions, imaging studies may still be necessary to rule out other serious causes. Computed tomography (CT) or magnetic resonance imaging (MRI) can check for structural abnormalities in the brain, such as tumors or vascular anomalies. Blood tests are used to exclude infections, metabolic disorders, or endocrine imbalances.
Neurological examinations will assess reflexes, muscle strength, and sensory functions to confirm whether there are signs of neurological impairment. In special circumstances, such as sudden worsening of headaches or accompanying consciousness disturbances, a lumbar puncture or angiography may be required. Although these examinations are not direct diagnostic tools for migraines, they can effectively rule out emergency conditions related to the central nervous system.
The International Classification of Headache Disorders (ICHD-3) is the core standard for diagnosing migraines. Physicians will determine whether the patient's symptoms and frequency of attacks meet the diagnostic criteria for "migraine." For example, ICHD-3 defines that migraine without aura requires at least five headache attacks that meet specific time and symptom combinations.
Auxiliary tools such as a headache diary can track symptom patterns, record triggers, and the severity of symptoms. The MIDAS scale (Migraine Disability Assessment) is used to assess the impact of headaches on work, family, and social life. These tools help physicians objectively quantify symptoms and develop personalized treatment plans.
Differential diagnosis must rule out other diseases that may cause similar symptoms. For instance, tension-type headaches are usually characterized by bilateral pressure sensations and lack the pulsating pain and sensitivity symptoms of migraines. Intracranial hemorrhage or brain tumors may be accompanied by neurological deficits and need to be confirmed through imaging studies. Cervical spine issues or temporomandibular joint disorders may also lead to head discomfort and need to be differentiated through physical examinations.
Additionally, diseases that need to be distinguished from migraines include intracranial arteritis, endometriosis-related headaches, and medication overuse headaches. Physicians will conduct differential analysis based on the acute or chronic nature of symptoms, pain characteristics, and changes in the course of the disease. For example, if headaches suddenly become severe and are accompanied by fever, the possibility of infectious diseases such as meningitis must be considered.
Early diagnosis can prevent unnecessary examinations and treatment delays. Prompt identification of the type of migraine allows patients to receive tailored relief and preventive treatments, reducing the frequency of acute attacks. For instance, chronic migraine patients who do not receive preventive medication early may gradually develop daily headaches, increasing treatment difficulty.
For patients, a clear diagnosis can reduce psychological stress and waste of medical resources. Physicians can also provide lifestyle adjustment recommendations through early assessments, such as stress management, regular routines, and trigger avoidance strategies. Long-term follow-up shows that patients diagnosed early have fewer emergency visits related to headaches, with overall quality of life improving by about 30-40%.
Physicians will first assess the patient's headache characteristics through interviews, including pain intensity, duration, accompanying symptoms (such as nausea and photophobia), etc. If necessary, brain MRI or CT scans may be arranged to rule out organic issues such as tumors or vascular anomalies, but not all patients require these imaging studies.
How can one distinguish migraines from general tension-type headaches?Migraine is often accompanied by pulsating pain, nausea, or sensitivity to light/sound, while tension-type headaches are mostly characterized by a sensation of pressure or tightness, usually without autonomic symptoms. Physicians will analyze the duration and frequency of symptoms based on the International Classification of Headache Disorders (ICHD) standards to differentiate.
Is it necessary to keep a headache diary for diagnosing migraines?Yes. Physicians often recommend that patients continuously record the timing of headache attacks, triggering factors (such as diet and stress), changes in symptoms, and medication responses. This helps confirm the diagnosis and develop personalized treatment plans, especially important for patients with atypical symptoms.
What special symptoms might prompt a physician to arrange brain imaging examinations?If a patient experiences sudden severe headaches (such as "thunderclap headache"), accompanied by neurological abnormalities (such as limb weakness), has their first attack after age 50, or has a history of cancer or autoimmune diseases, the physician will prioritize arranging MRI or CT scans to rule out other serious causes.
Is blood testing necessary for migraine diagnosis?Generally, routine blood tests are not required, but if a patient's headache pattern changes suddenly, accompanied by unexplained fever or weight loss, the physician may arrange blood tests to rule out potential issues such as infections, autoimmune diseases, or metabolic disorders.