Stroke Treatment and Management

The treatment of stroke needs to be tailored to the severity of the patient's condition, the time of onset, and the type of lesion. The treatment goals are to immediately restore blood flow to the brain, reduce brain cell damage, and prevent subsequent complications. Modern medicine combines various strategies such as medication, surgery, rehabilitation, and lifestyle management to enhance the chances of patient recovery.

The acute phase of treatment is particularly critical, especially when action is taken within the "golden treatment window" of a few hours after the onset, which can significantly improve prognosis. Treatment strategies must be differentiated based on the type of stroke (ischemic or hemorrhagic) and combined with long-term preventive measures to reduce the risk of recurrence. Rehabilitation therapy and psychological support are also important aspects of the recovery process.

Current Treatment Options

Current stroke treatment can be divided into three main stages: acute emergency treatment, subacute rehabilitation, and long-term management. The primary goal of acute treatment is to "clear blocked blood vessels" or "stop bleeding"; for example, ischemic stroke patients may receive thrombolytic agent injections, while hemorrhagic stroke requires surgical removal of hematomas or repair of vascular abnormalities.

Subacute treatment focuses on functional rehabilitation, including physical therapy, speech therapy, and occupational therapy, to assist patients in regaining their ability to perform daily activities. Long-term management emphasizes controlling risk factors such as hypertension and diabetes, combined with medication and lifestyle adjustments to reduce the likelihood of secondary strokes.

Medication Treatment

Acute Phase Medications

Ischemic stroke patients who seek medical attention within 4.5 hours of onset may qualify for the use of tissue plasminogen activator (tPA). This medication can dissolve blood clots but requires strict assessment of bleeding risks. Antiplatelet medications such as aspirin or prasugrel can inhibit platelet aggregation and are commonly used for treatment beyond 24 hours after onset.

  • Thrombolytic agents (tPA): Must be used within the golden time window and can reduce disability rates by about 30%.
  • Anticoagulants: Such as warfarin or new oral anticoagulants (NOACs), used to prevent cardiogenic embolism in patients with atrial fibrillation.
  • Antihypertensives: Controlling hypertension can reduce the risk of secondary bleeding, but excessive lowering of blood pressure should be avoided to prevent affecting cerebral perfusion.

Chronic Phase Medications

Long-term use of lipid-lowering medications such as statins can stabilize atherosclerotic plaques and reduce the risk of arterial blockage. Diabetic patients need to use insulin or oral hypoglycemic agents to maintain stable blood sugar levels and prevent worsening of vascular damage.

Non-Pharmacological Therapies

Surgical Treatment

Endovascular therapy is an invasive option for ischemic stroke, including mechanical thrombectomy or stenting. This method is suitable for patients with large vessel occlusion who do not respond well to medical treatment, allowing for direct removal of clots via catheter. Hemorrhagic stroke may require craniotomy to remove hematomas or aneurysm clipping to prevent rebleeding.

Rehabilitation Therapy

Physical therapists design customized exercise programs to help restore strength and balance. Speech therapists create training for patients with aphasia, gradually restoring communication abilities through verbal practice and alternative communication tools. Occupational therapy teaches patients to use assistive devices, such as canes or walkers, to enhance their ability to live independently.

Lifestyle Management

Lifestyle adjustments are a core strategy for preventing secondary strokes. It is recommended to adopt the DASH diet, reducing high-sodium and high-fat foods while increasing whole grains and fruit and vegetable intake. Regular monitoring of blood pressure, blood sugar, and lipid levels is key to delaying vascular changes.

  • Smoking cessation: Nicotine constricts blood vessels and accelerates atherosclerosis; quitting smoking can reduce the risk of recurrence by up to 50%.
  • Regular exercise: Engaging in 150 minutes of moderate-intensity exercise weekly, such as brisk walking or swimming, can improve cardiovascular function.
  • Limit alcohol: Men should limit alcohol intake to no more than 2 units per day, while women should limit to 1 unit, to avoid triggering blood pressure fluctuations.

Future Treatment Directions

Gene therapy and stem cell therapy are current research hotspots. Stem cell transplantation aims to repair damaged brain tissue, while gene editing technology may correct genetic defects that lead to atherosclerosis. Additionally, artificial intelligence-assisted diagnostic systems can interpret images more accurately, helping physicians make quick decisions.

Clinical trials for new antiplatelet medications and anticoagulants are ongoing, such as studies on dose adjustments for direct oral anticoagulants (DOACs). Although neuroprotectants are not yet mature, their mechanisms of inhibiting apoptosis pathways are still considered a potential breakthrough direction.

When to Consult a Specialist

If symptoms such as unilateral limb weakness, slurred speech, or visual disturbances occur, immediate medical attention is required. Even if symptoms temporarily disappear, a comprehensive assessment should be conducted at a neurology clinic. Patients diagnosed with stroke should be followed up every 3-6 months to assess medication response and vascular status.

Immediate emergency medical attention is needed in the following situations:
1. Generalized seizures or altered consciousness
2. Blood pressure sharply rising above 180/120 mmHg
3. Sudden memory loss accompanied by disorientation

 

Frequently Asked Questions

Why do acute stroke patients need to receive treatment within the "golden three hours"?

The golden time for stroke treatment mainly targets ischemic strokes; patients receiving thrombolytic therapy (such as tissue plasminogen activator) within 3 hours of symptom onset can significantly increase the chances of recanalization and reduce the risk of permanent neurological damage. Delaying treatment may lead to irreversible damage due to prolonged ischemia of brain cells.

What are the differences in treatment strategies for different types of strokes?

Ischemic strokes typically focus on dissolving or removing clots, while hemorrhagic strokes require controlling intracranial pressure, stopping bleeding, or surgically removing hematomas. Treatment methods vary based on the cause; for example, antiplatelet medications are suitable for atherosclerotic strokes, while cardiogenic strokes may require combined cardiac disease treatment, necessitating a personalized plan developed by the medical team.

When is the most effective time to begin rehabilitation after a stroke?

Early rehabilitation should begin once the acute phase is stabilized, typically during hospitalization, with therapists intervening to provide physical therapy, occupational therapy, and speech therapy. Early intervention can promote neuroplasticity, restoring mobility and independence, but the specific timeline should be adjusted based on the patient's degree of neurological impairment and overall health status.

Do stroke patients need to continue taking medication after discharge? What are common medications?

Yes, patients need to continue taking antiplatelet medications (such as aspirin), lipid-lowering medications (such as statins), or antihypertensives as prescribed to reduce the risk of recurrence. Physicians may adjust the medication combination based on complications, and patients should regularly return for check-ups to monitor physiological indicators and should not stop taking medications on their own.

How effective is acupuncture in helping with post-stroke sequelae?

Current evidence suggests that acupuncture can serve as an adjunct therapy in stroke rehabilitation, potentially improving symptoms of limb weakness or numbness, but it should be used alongside Western medical treatment and not replace acute emergency measures. Research recommends that it be conducted under the supervision of professional traditional Chinese medicine practitioners and rehabilitation teams to ensure safety and effectiveness.

Stroke